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跨性别女性遵守口服预暴露预防干预措施:系统性审查

Jorge Eduardo Moncayo¹, María Del Mar Pérez-Arizabaleta^1,2, Lina María Villegas-Trujillo^3,4

¹Faculty of Psychology, Universidad Antonio Nariño, Cali, Colombia.

AIDS education and prevention : official publication of the International Society for AIDS Education

|October 16, 2023

概括

在跨性别女性中,预防艾滋病毒的暴露前预防 (PrEP) 的遵守率很低. 提高对PrEP的认识和教育,特别是关于性别肯定激素治疗,对这一群体至关重要.

科学领域:

公共卫生公共卫生
传染性疾病传染性疾病
预防艾滋病毒/艾滋病预防

背景情况:

变性人群表现出更高的人类免疫缺陷病毒 (HIV) 的流行率.
暴露前预防 (PrEP) 是减少艾滋病毒感染的有效干预措施.
了解跨性别女性 (TW) 遵守口服PrEP对于有效的艾滋病毒预防策略至关重要.

研究的目的:

调查艾滋病毒阴性跨性别女性 (TW) 中口服预暴露预防 (PrEP) 的坚持率.
为了将TW的坚持与与男性发生性关系的 cisgender男性 (cMSM) 进行比较.

主要方法:

基于"柯克兰手册"和PRISMA声明的系统审查方法.
在多个数据库中进行全面的文献搜索:科学网,OVID,Scopus,MEDLINE和Cochrane控制试验中央注册表.
坚持测量主要依赖于自我报告 (72.7%) 和干血点检测 (45.5%).

主要成果:

与与男性发生性关系的 cisgender 男人 (cMSM) 相比,跨性别女性 (TW) 参与和遵守口服 PrEP 发现较低.
该研究发现,大量依赖于自我报告的坚持数据.
泰国两项涉及TW性工作者的研究严重影响了样本大小.

结论:

需要提高跨性别女性对口服PrEP的认识.
在试验开始时,教育TW关于口服PrEP对性别肯定激素治疗的潜在影响至关重要.
未来的研究应该探索超越口服配方的新型PrEP方式的坚持.

关键词:

艾滋病病毒艾滋病病毒艾滋病病毒坚持性坚持性暴露前的预防暴露前的预防跨性别女性,跨性别女性.

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