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Updated: Jul 13, 2025

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice
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瘤反应性CD8+ T细胞进入TCF1+PD-1-功能障碍状态

Jessica J Roetman1, Megan M Erwin1, Michael W Rudloff1

  • 1Department of Medicine, Division of Hematology and Oncology, Vanderbilt University School of Medicine, Nashville, Tennessee.

Cancer immunology research
|October 16, 2023
PubMed
概括

瘤特异性T细胞 (TST) 持续存在并耗尽,而自我/共享抗原特异性T细胞 (SST) 从瘤中消失. 了解这种抗原特异性T细胞分化是改善癌症免疫治疗和减少副作用的关键.

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