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结核菌抑制APLP2的表达,以提高其在巨细胞中的存活率

Jianxia Chen1, Fen Tang1, Haohao Li1

  • 1Clinical and Translational Research Center, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, China; Shanghai Key Lab of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, China.

International immunopharmacology
|October 16, 2023
PubMed
概括

粉样蛋白前体样蛋白2 (Aplp2) 对于控制结核病至关重要. 较低的Aplp2水平损害了巨细胞的防御能力,增加了对Mycobacterium tuberculosis (M.tb) 感染的易感性.

关键词:
Aplp2p2 在线播放细胞因子的生产生产.在M.T.B.T. 里面.NF-κB的转录活动.

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