体质指数与败血症老年人死亡率之间的关联
Na Li1, Ling Tian2, Qiang Zhou3
1Hekou District People's Hospital, Department of Anesthesiology, Dongying City, Shandong, China.
Geriatric nursing (New York, N.Y.)
|October 16, 2023
概括
较高的体重指数 (BMI) 与败血症老年人的更好的生存率有关,而体重不足会增加死亡风险. 与女性相比,BMI较高的男性患者的死亡率较低.
科学领域:
- 老年学是一门学科.
- 关键护理医学 关键护理医学
- 流行病学 流行病学
背景情况:
- 关于身体质量指数 (BMI) 与患有败血症的老年人结局之间的关联的证据有限.
- 老年人群中的败血症带来了独特的挑战,需要研究像BMI这样的预后因素.
研究的目的:
- 调查体质指数 (BMI) 与被诊断患有败血症的老年人临床结果之间的关系.
- 为了确定BMI是否影响老年败血症患者的30天死亡率.
主要方法:
- 从MIMIC-IV数据库对6604名患有败血症的老年人 (年龄≥65岁) 的回顾性分析.
- 使用多变量逻辑回归来评估BMI与30天死亡率之间的关联.
- 分层分析探讨了性别,种族,病,充血性心力衰竭,糖尿病和慢性肺病的相互作用.
主要成果:
- 在对共变量进行调整后,在BMI和30天死亡率之间发现了显著的反相关性.
- 每增加1kg/m2的BMI与30天死亡率下降3%有关 (调整HR=0.97).
- 观察到BMI和死亡率之间存在非线性,L形的关联,性别有显著的相互作用.
结论:
- 更高的BMI与患有败血症的老年人生存率的改善有关.
- 体重不足与这一群体的死亡风险增加有关.
- 男性败血症患者的BMI较高,死亡风险低于女性患者.
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