使用非扭曲的IVIM来减少在鼻MRI中对比剂的需要
Rui Chen1, Huifen Ye1, Zhigang Wu2
1Department of Radiology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou 510080, China; Guangdong Provincial Key Laboratory of Artificial Intelligence in Medical Image Analysis and Application, Guangzhou 510080, China.
Magnetic resonance imaging
|October 16, 2023
概括
非扭曲的Intravoxel不连贯运动 (IVIM) 成像为鼻癌 (NPC) 随访提供了对比度增强的T1加权成像 (CE-T1WI) 的有希望的替代方案. 这种先进的IVIM技术减少了图像扭曲,并可以预测瘤增强,从而最大限度地减少了加多暴露.
科学领域:
- 医疗成像医学成像
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
背景情况:
- 鼻癌 (NPC) 随访中的对比增强型MRI风险是神经组织中的加多沉积.
- 寻求非对比增强方法来预测T1加权成像 (T1WI) 增强,避免对比剂.
- 传统的intravoxel不连贯运动 (IVIM) 在NPC患者中遭受严重的扭曲和信号损失.
研究的目的:
- 评估非扭曲IVIM是否可以减少在NPC后续中对比度增强T1加权成像 (CE-T1WI) 的需要.
- 评估非扭曲IVIM参数对CE-T1WI增强的预测能力.
主要方法:
- 在NPC患者身上进行了基于扩散权重成像的IVIM (非扭曲IVIM) 的Turbo Spin-echo MVXD.
- 非扭曲IVIM的扭曲率 (DR) 与传统IVIM进行了比较.
- 相关性和线性回归分析评估了非扭曲IVIM参数和CE-T1WI增强之间的关系.
主要成果:
- 非扭曲IVIM与传统IVIM相比显示出明显较低的扭曲率 (0.12 ± 0.05与0.48 ± 0.16相比,P < 0.001).
- 在非扭曲的IVIM参数"f"和CE-T1WI增强比率 (r = 0.543,P = 0.011) 之间发现了显著的相关性.
- 线性回归证实"f"是NPC患者CE-T1WI增强的独立预测因子 (P = 0.011).
结论:
- 非扭曲IVIM在减少NPC随访对比剂要求方面显示出潜在的临床实用性.
- 这种方法可以独立预测增强比率,提供一种有价值的非对比替代方案.
- 减少扭曲和预测能力突显了IVIM对NPC患者管理的非扭曲益处.
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