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相关概念视频

Bone Remodeling01:40

Bone Remodeling

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Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
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Bone Disorders01:29

Bone Disorders

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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
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相关实验视频

Updated: Jul 13, 2025

Bioelectric Analyses of an Osseointegrated Intelligent Implant Design System for Amputees
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开发一种运动干预措施,以改善创伤截肢患者的骨矿物质密度:德尔菲研究的协议.

Fearghal P Behan1, Anthony M J Bull2, Alexander Bennett3

  • 1Department of Bioengineering, Imperial College London, London, UK F.Behan@imperial.ac.uk.

BMJ open
|October 16, 2023
PubMed
概括

这项研究旨在制定运动指南,以改善截肢者的骨矿物质密度 (BMD). 专家将使用德尔菲技术,就运动参数达成共识,以最大限度地减少下肢截肢患者的BMD损失.

关键词:
骨疾病 骨疾病肌肉骨系统疾病 肌肉骨系统疾病预防性医学 预防性医学康复医学是康复的医学.运动医学运动医学

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Longitudinal Evaluation of Mouse Hind Limb Bone Loss After Spinal Cord Injury using Novel, in vivo, Methodology
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科学领域:

  • 生物医学工程 生物医学工程
  • 整形外科 整形外科 整形外科
  • 运动生理学 运动生理学

背景情况:

  • 下肢截肢导致受影响侧的骨矿物质密度 (BMD) 降低.
  • 运动干预措施是有效改善BMD,但尚未专门开发或测试截肢者.
  • 由于肢体损失和假肢接口挑战,现有的练习可能不适合截肢者.

研究的目的:

  • 征求专家意见,并就运动处方参数达成共识.
  • 定义减少或恢复截肢者骨密度 (BMD) 损失的策略.
  • 为了告知未来的运动干预试验对截肢人群的发展.

主要方法:

  • 利用德尔菲技术在国际专家之间建立远程共识.
  • 进行多轮的e-Delphi流程,使用5点的利克特级别来对协议进行评级.
  • 在未来试验中实施的陈述中,建立≥70%的同意率的共识.

主要成果:

  • 将就截肢者的特定运动处方参数达成共识.
  • 该研究将为运动干预制定可行的指导方针.
  • 专家的同意将通过对利克特比例表答案的统计分析来量化.

结论:

  • 这项研究将为截肢者提供基于证据的炼建议,以解决骨损失.
  • 这些发现将有助于为下肢截肢的人设计有针对性和安全的运动计划.
  • 建立共识是改善截肢人口骨健康结果的关键一步.