在初级保健中,便免疫化学测试的吸收率的社会人口统计学变化:一项回顾性研究
James A Bailey1, Alastair J Morton2, James Jones3
1Nottingham Colorectal Service, Nottingham University Hospitals NHS Trust; School of Medicine, University of Nottingham, Nottingham.
社会人口统计学因素对症状患者的便免疫化学测试 (FIT) 返回率产生重大影响. 需要制定战略,以确保公平的结肠直肠癌 (CRC) 查,因为FIT的使用越来越多.
科学领域:
- 胃肠病学和肝病学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 便免疫化学测试 (FIT) 越来越多地用于症状患者检测结直肠癌 (CRC).
- 基于社会人口统计学因素的FIT使用变化并未得到充分理解.
- 2017年实施了CRC的初级保健临床途径,为GP提供了直接访问FIT的机会.
研究的目的:
- 研究社会人口统计学因素对症状患者中FIT复发率的影响.
- 为了确定在英国初级保健环境中FIT完成的潜在差异.
主要方法:
- 从2017年11月到2021年12月在英国诺丁汉的患者转诊的回顾性分析.
- 多变量后勤回归用于分析影响FIT回报的社会人口因素.
- FIT是对结直肠转诊的强制性分类工具,与血液样本和费里丁一起用于分层CRC风险.
主要成果:
- 90.7%的患者返回了他们的FIT,而9.3%的人没有.
- 男性 (OR 1.11) 和最贫困的五分之一 (OR 2.20) 的患者不太可能恢复FIT.
- 老年患者 (≥65岁) 更有可能返回FIT (或0.78不返回),而少数民族更有可能与白人患者相比不返回FIT.
结论:
- 怀疑CRC的FIT回报率因性别,年龄,种族和社会经济地位而异.
- 解决这些差异的策略对于公平的CRC检测至关重要,因为FIT使用范围正在扩大.
- 需要进一步的研究来优化FIT协议并改善患者在不同人群中的坚持.
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