确定影响癌症儿童化疗诱导的恶心和吐的因素
Ayşe Ay1, Handan Boztepe2, Sevil Çınar Özbay3
1Department of Nursing, Faculty of Health Sciences, Başkent University, Ankara, Turkey.
Journal of pediatric nursing
|October 16, 2023
概括
儿童的化疗诱导性恶心和吐 (CINV) 受与儿童,治疗和父母相关的因素的影响. 减少焦虑,为儿童和家长提供教育,可以帮助管理CINV.
科学领域:
- 儿科瘤学 儿科瘤学
- 临床心理学 临床心理学
- 药理学 药理学是指药理学的学科.
背景情况:
- 化疗诱导的恶心和吐 (CINV) 是接受癌症治疗的儿童常见和令人痛苦的副作用.
- 了解CINV的多因素性质对于开发有效的管理策略至关重要.
研究的目的:
- 确定和评估影响儿童癌症患者中CINV发生的关键因素.
- 探索儿童相关,治疗相关和父母相关因素在CINV中的作用.
主要方法:
- 一项涉及62名患有固体瘤的儿童 (年龄9-18岁) 的横截面研究,他们接受了第一次化疗疗程.
- 数据收集包括经过验证的焦虑库存 (儿童州道焦虑库存,贝克焦虑库存,斯皮尔伯格州道焦虑库存) 和巴克斯特缩面部量表.
- 统计分析使用斯皮尔曼的相关性和物流回归来确定风险因素.
主要成果:
- 儿童相关因素:诊断,诊断后的时间,治疗前的焦虑,以及之前的恶心/吐史显著影响了CINV.
- 与治疗相关的因素:抗emetic预防是一个重要的预测因素.
- 父母相关的因素:治疗前的父母焦虑,住宿,饮食摄入 (不吃饭) 和环境因素 (恶臭) 与CINV有关.
结论:
- 儿童的CINV受到儿童,治疗和父母相关因素的组合的显著影响.
- 儿科护士通过减少焦虑和教育家庭管理策略,在缓解CINV方面发挥着至关重要的作用.
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