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Updated: Jul 13, 2025

Synthesis of 1,2-Azaborines and the Preparation of Their Protein Complexes with T4 Lysozyme Mutants
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Published on: March 25, 2017

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结构优化抗菌性阿扎乌龙,以提高溶解性和代谢稳定性

André Campaniço1, Shrika G Harjivan1, Elisabete Freitas1

  • 1Instituto de Investigação do Medicamento (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003, Lisboa, Portugal.

ChemMedChem
|October 16, 2023
PubMed
概括

新的N-carbamoyl azaaurones显示出对结核病 (TB) 和耐药菌株的强烈抗菌活性. 这些化合物表现出更好的代谢稳定性和溶解性,提供了有前途的治疗潜力.

关键词:
在M.结核病.亚萨奥罗尼斯 (azaaurones) 是一种气质的石头.发现药物的发现.耐药结核病的治疗方法结构 - 活动关系结构 - 活动关系

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