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Updated: Jul 13, 2025

Characterizing Exon Skipping Efficiency in DMD Patient Samples in Clinical Trials of Antisense Oligonucleotides
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Published on: May 7, 2020

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渐进的超核性麻中意想不到的性别差异揭示了davunetide对女性的疗效

Illana Gozes1, Guy Shapira2, Alexandra Lobyntseva3

  • 1Elton Laboratory for Molecular Neuroendocrinology, Department of Human Molecular Genetics and Biochemistry, Faculty of Medicine, Adams Super Center for Brain Studies and Sagol School of Neuroscience, Tel Aviv University, 69978, Tel Aviv, Israel. igozes@tauex.tau.ac.il.

Translational psychiatry
|October 16, 2023
PubMed
概括

达文提德通过增强微管相互作用,特别是在女性中,在治疗渐进性超核性 (PSP) 中表现出有效性. 这种病药物表现出神经保护作用,并减缓了女性的疾病进展,解决了之前的疗效问题.

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