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饮食中的宏观营养素摄入量与生物衰老之间的关系:对NHANES数据的横截面分析

Xu Zhu^1,2, Jing Xue³, Rehanguli Maimaitituerxun⁴

¹Department of Nephrology, Xiangya Hospital, Central South University, No.87 Xiangya Road, Kaifu District, Changsha, 410008, Hunan, China.

European journal of nutrition

|October 16, 2023

概括

食纤维,优质的碳水化合物,植物蛋白质和omega-3脂肪酸可以防止生物衰老加速. 相反,低质量的碳水化合物和和脂肪可能会增加它,这表明饮食改变可以改善健康.

科学领域:

营养科学营养科学
老年学是指老年学的学科.
生物统计学生物统计学

背景情况:

生物年龄,生理健康的衡量标准,可以相对于时间年龄来说加速或减缓.
宏观营养素摄入量是一个可改变的因素,可能会影响生物衰老过程.

研究的目的:

在大量成年人群中调查宏观营养素摄入量与生物衰老加速 (AA) 之间的关联.

主要方法:

利用来自美国国家健康和营养检查调查 (NHANES) 的26381名美国成年人的数据.
使用Klemera-Doubal方法 (KDM) 和PhenoAge算法估计的生物年龄.
计算了生物衰老加速 (AA) 和分析了与饮食中巨量营养素摄入量的关联.

主要成果:

食纤维,高质量的碳水化合物,植物蛋白和omega-3多不和脂肪酸 (PUFA) 与AA的降低有关.
低质量的碳水化合物和长链和脂肪酸 (SFA) 与AA的增加有关.
经过调整以考虑混因素后,关联仍然很重要.

结论:

富含纤维,优质碳水化合物,植物蛋白和欧米茄-3 PUFA 的饮食模式可能会对加速生物衰老产生保护作用.
相反,高含低质量的碳水化合物和长链SFAs的饮食可能会促进更快的生物衰老.
通过饮食干预来改变宏观营养素摄入量可能是预防与年龄有关的疾病和改善整体健康的策略.

关键词:

生物衰老生物衰老横截面研究横截面研究大量营养素宏观营养素尼汉斯 (NHANES) 是一个名人.

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