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Oral Health Assessment by Lay Personnel for Older Adults
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老年人认知功能,口腔状况和全身代谢功能之间的关系

Kenji Karako1, Yu Chen2, Katsunori Oyama3

  • 1Department of Human and Engineered Environmental Studies, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Japan. k.karako@edu.k.u-tokyo.ac.jp.

Advances in experimental medicine and biology
|October 16, 2023
PubMed
概括

保持良好的口腔健康可以预测老年人的认知能力下降. 较少的牙和更多缺失的假牙表明口腔健康状况不佳,这与较高的认知障碍风险有关,特别是在考虑全身代谢功能时.

关键词:
认知功能 认知功能口腔健康 口腔健康是指口腔健康.系统代谢功能 系统代谢功能

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科学领域:

  • 老年学是指老年学的学科.
  • 口腔健康 口腔健康
  • 神经学 神经学

背景情况:

  • 系统代谢障碍和与生活方式相关的疾病是痴呆症的确立危险因素.
  • 口腔疾病,如牙周病和牙,与代谢障碍有关,可能表明痴呆风险.
  • 在老年人中,口腔健康,全身代谢功能和认知衰退之间的相互作用需要进一步研究.

研究的目的:

  • 在老年人群中调查认知功能,口腔健康状况和全身代谢功能之间的关系.
  • 评估深度学习模型在估计基于代谢数据及其与口腔健康相关性的认知功能的有效性.

主要方法:

  • 该研究涉及41名老年参与者 (平均年龄为69.7岁).
  • 通过计算健康的牙,假牙和缺失的假牙来评估口腔健康.
  • 认知功能使用迷你精神状态检查 (MMSE) 测量,并通过使用基本血液测试数据的深度学习模型估计.

主要成果:

  • 深度学习估计的MMSE得分与健康牙数量 (r=0.37) 有正相关性,与缺失假牙 (r=-0.39) 有负相关性.
  • 估计的认知功能与年龄负相关,与需要假牙的牙数量正相关,这也与与生活方式相关的疾病相关.
  • 测量的MMSE得分和口腔健康指标之间没有发现显著的相关性,这表明深度学习方法更好地捕捉了代谢-口腔-认知联系.

结论:

  • 口腔健康状况,特别是天然牙和缺失假牙的数量,可能成为老年人认知障碍的预测因素.
  • 基于深度学习的认知功能估计,反映了全身代谢状态,突出了口腔健康和认知衰退风险之间的强烈关联.
  • 系统代谢功能可能会影响口腔健康和认知功能,这强调了综合健康评估的重要性.