评估儿童艾滋病毒药物口服溶解条的设计特征的用户偏好:一个定性研究
Catherine Wexler1, May Maloba2, Michala Sliefert3
1Department of Family Medicine, University of Kansas Medical Center, Kansas City, KS, USA. cwexler@kumc.edu.
BMC health services research
|October 16, 2023
概括
口服溶解条为当前婴儿抗逆转录病毒疗法 (ART) 配方提供了一个有希望的替代方案. 护理人员和提供者强烈喜欢这些条带,以改善艾滋病毒感染儿童的坚持和结果.
科学领域:
- 儿童传染病 儿童传染病
- 制药配方的开发和发展
- 全球卫生健康 全球卫生健康
背景情况:
- 目前的婴儿抗逆转录病毒疗法 (ART) 配方存在重大坚持挑战,包括复杂的剂量和糟糕的可口性,导致潜在的病毒学失败和耐药性.
- 口服可溶性条纹已被确立为儿科ART的可行替代品,旨在改善粘附性和患者的治疗结果.
研究的目的:
- 评估护理人员和提供者对口服溶解条及其包装的偏好,以告知产品开发.
- 收集以用户为中心的设计输入,以优化儿科抗逆转录病毒药物治疗.
主要方法:
- 以用户为中心的设计方法,利用与30名艾滋病毒护理提供者的关键信息人采访.
- 与肯尼亚72名10岁以下艾滋病毒感染儿童的照顾者进行了焦点小组讨论.
- 所有定性数据的音频录制,字面转录和主题编码.
主要成果:
- 强烈的护理人员和提供者对口服溶解条的热情,特别是对于无法吞药片的幼儿.
- 关键的偏好包括愉快的味道,单剂量条,迅速溶解,明确的说明和没有特殊的储存.
- 首选的包装:单独包装,耐用,防水条带在可重复使用的配剂器内,容易让孩子打开.
结论:
- 口服可溶性条对于艾滋病毒感染儿童的护理人员和提供者来说是非常可接受的.
- 让利益相关者参与代设计将最大限度地提高开发可接受和可持续的增强粘附性的产品的可能性.
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