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Updated: Jul 13, 2025

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形式跟随功能:核形态作为细胞衰老的可量化的预测因素

Jakub Belhadj1,2, Surina Surina1,2,3, Markus Hengstschläger1

  • 1Center for Pathobiochemistry & Genetics, Institute of Medical Genetics, Medical University of Vienna, Vienna, Austria.

Aging cell
|October 17, 2023
PubMed
概括

核的形状变化预测了细胞衰老. 深度学习使用核形态学准确地将细胞分类为增殖或衰老,有助于疾病研究.

关键词:
人工智能的人工智能是人工智能.细胞核的细胞核.细胞生物物理学的细胞生物物理.细胞衰老 细胞衰老计算机视觉 计算机视觉机器学习是机器学习.形态发生 (morphogenesis) 是一种形态的产生.定量显微镜 定量显微镜

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Replicative cell senescence is a property of cells that allows them to divide a finite number of times throughout the organism's lifespan while preventing excessive proliferation. Replicative senescence is associated with the gradual loss of the telomere — short, repetitive DNA sequences found at the end of the chromosomes. Telomeres are bound by a group of proteins to form a protective cap on the ends of chromosomes. Embryonic stem cells express telomerase — an enzyme that adds...
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