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临床应用的关键闪的融合频率在光神经炎脱髓化的视觉神经炎

Junxia Fu¹, Yongping Wang¹, Shaoying Tan²

¹Department of Ophthalmology, The Chinese People's Liberation Army General Hospital & The Chinese People's Liberation Army Medical School, Beijing, China.

Advances in ophthalmology practice and research

|October 17, 2023

概括

临界闪融合频率 (CFF) 显著降低于脱髓化视神经炎 (DON) 患者,与视觉功能障碍相关. 通过CFF测量,可以有效地评估DON的视觉功能障碍.

科学领域:

眼科医生眼科眼科
神经科学是一个神经科学.
视觉电生理学视觉电生理学

背景情况:

脱线光神经炎 (DON) 是一种影响视神经功能的疾病.
评估DON患者的视觉功能障碍对于患者的管理和治疗疗效至关重要.
临界闪融合频率 (CFF) 是视觉处理速度的度量.

研究的目的:

评价CFF在测量视力障碍患者的视力神经炎 (DON) 的实用性.
探索CFF与其他已确定的DON视觉功能指标之间的相关性.

主要方法:

一项涉及69名DON患者和33名健康对照 (HC) 的横截面研究.
评估包括最佳校正的视敏度 (BCVA),视野,光学连贯性断层扫描 (OCT),闪光视觉唤起潜力 (F-VEP) 和CFF.
DON患者按抗体类型 (AQP4-,MOG-,双阴性),视敏度严重程度和从发病到检查的时间分组.

主要成果:

与HC相比,DON患者的CFF值显著降低.
在严重视敏度损伤的患者中,CFF减少最为明显.
在发病后的时间内,CFF值显示出显著的差异,在3个月后稳定.
CFF与F-VEP延迟和BCVA有显著的负相关性,与平均视野缺陷 (MD) 有正相关性.

结论:

在DON受影响的眼睛中,CFF显著下降.
CFF测量与BCVA,MD和F-VEP延迟有很好的相关性.
CFF 作为一个有价值的工具,用于评估视觉功能障碍在脱髓化视神经炎.

关键词:

关键的闪融合频率是什么?视觉神经炎的脱线化.

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