儿科角膜交叉连接当前的策略:一个审查
Pawan Prasher1, Ashok Sharma2, Rajan Sharma2
1Department of Ophthalmology, Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, Punjab, India.
Advances in ophthalmology practice and research
|October 17, 2023
概括
角膜原交叉连接可以阻止儿童的角质进展. 德累斯顿协议是有效的,但加速或跨体方法提供了具有不同结果的替代方案.
科学领域:
- 眼科医生 眼科 眼科
- 角质细胞疾病 角质细胞疾病
背景情况:
- 在2000人中,有1人患有角,东南亚人患病率更高.
- 儿童较早出现较严重的角,眼睛摩擦是危险因素.
- 儿童的进展很快,使视觉康复具有挑战性,并且通常需要早期的角质形成.
研究的目的:
- 评估角膜原交叉链接 (CXL) 在阻止儿童角膜进展方面的有效性.
- 为了比较不同的CXL协议,包括德累斯顿协议,加速CXL和体CXL.
主要方法:
- 德累斯顿协议涉及中枢角膜去皮质化, рибофлавин和和UV-A暴露.
- 加速CXL减少了手术时间,而横CXL避免了脱皮质化.
- 在治疗之前,应先管理春季角膜结膜炎.
主要成果:
- 角膜原交叉连接是安全和有效的,可以阻止儿童的角质进展.
- 德累斯顿协议非常成功,但有缺点,如长时间的操作时间和疼痛.
- 加速CXL在一些研究中同样有效,而体CXL更安全但效果较差.
结论:
- 建议使用德累斯顿协议,以阻止儿科形的进展.
- 加速CXL是一种可行的更快的替代方案.
- 穿体CXL提供了安全益处,但降低了稳定功效.
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