弹性建设能源管理计划对系统性硬化症疲劳和其他症状的影响:随机对照试验
Susan L Murphy1, Yen T Chen1, Mary Alore1
1University of Michigan, Ann Arbor.
Arthritis care & research
|October 17, 2023
概括
一个建立性的能量管理计划 (RENEW) 显著改善了系统性硬化症患者的疲劳和其他结果. 这种mHealth干预表明,SSc症状管理中的广泛可扩展性具有前景.
科学领域:
- 类风湿病学 类风湿病学
- 数字健康数字健康
- 患者报告的结果
背景情况:
- 系统性硬化症 (SSc) 的管理需要有效的支持自我管理干预措施.
- 疲劳对于SSc.患者来说是一个重大挑战.
研究的目的:
- 评估12周的弹性建设能源管理计划 (RENEW) 对SSc患者疲劳和其他结果的影响.
- 评估mHealth支持的干预措施对系统性硬化症症状管理的有效性.
主要方法:
- 173名中度至严重疲劳的SSc患者被随机分配 (2:1) 给RENEW干预或等候名单对照.
- 该RENEW计划包括一个教育网站/应用程序和一个为期12周的虚拟同行领导的健康辅导课程.
- 结果,包括疲劳 (FACIT-Fatigue),疼痛干扰,抑郁症状和性,在基线,6周和12周被评估.
主要成果:
- 与对照组相比,RENEW参与者在疲劳方面表现出了临床上有意义的改善 (P < 0.001).
- 在所有二次结果中观察到显著的改善,包括疼痛干扰,抑郁症状和性.
- 疾病持续时间较短的患者在RENEW组中经历了更大的疲劳改善.
结论:
- 由mHealth支持的RENEW干预有效改善了系统性硬化症疲劳和其他患者报告的结果.
- 该计划的设计表明在管理SSc症状方面具有广泛可扩展性的潜力.
- 早期诊断可能与这种自我管理方法的更大好处有关.
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