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Updated: Jul 13, 2025

A Microwave-Assisted Direct Heteroarylation of Ketones Using Transition Metal Catalysis
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调节中链脱酶/还原酶的立体选择性,通过创建一个额外的活性口袋来容纳亲切的异环基

Lei Qin1, Xin Su1, Jun Wang1

  • 1Laboratory of Brewing Microbiology and Applied Enzymology, School of Biotechnology and Key Laboratory of Industrial Biotechnology of Ministry of Education, Jiangnan University, Wuxi 214122, China. ynie@jiangnan.edu.cn.

Chemical communications (Cambridge, England)
|October 17, 2023
PubMed
概括

研究人员设计了一种中链脱酶/还原酶 (MDR) 酶,以控制异环基的立体选择性还原. 这一突破增强了性酒精的合成,这对药物开发至关重要.

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