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Updated: Jul 13, 2025

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一个ULK1/2-PXN机械传导途径抑制了乳腺癌细胞迁移

Peigang Liang1, Jiaqi Zhang1, Yuchen Wu1

  • 1State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, China.

EMBO reports
|October 17, 2023
PubMed
概括

自诱导激酶ULK1/2通过控制机械转导来调节乳腺癌细胞迁移. ULK1/2可酸化帕克西林,破坏焦点粘附并改变细胞对机械线索的反应.

关键词:
在PXN/Paxillin中使用.在ULK1/2中.乳腺癌细胞迁移 细胞迁移焦点粘附的焦点粘附.机械传导 机械传导

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