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Published on: October 15, 2021
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COVID-19对内出血和手术结果的影响:综合分析
Samil Dikici1, Baris Colluoglu
1Ministry of Health, Basaksehir Cam and Sakura City Hospital, Department of Neurosurgery, Istanbul, Turkey.
Turkish neurosurgery
|October 17, 2023
概括
这项研究发现,虽然手术显著改善了脑内膜内出血 (IPH) 患者的血瘤体积和中线转移,但COVID-19感染并没有影响死亡率. 然而,COVID-19阳性患者的生存时间趋于缩短.
科学领域:
- 神经外科 神经外科
- 传染性疾病 传染性疾病
- 神经学 神经学
背景情况:
- 肠膜内出血 (IPH) 是一种严重的神经疾病.
- COVID-19感染对IPH结果的潜在影响需要进行调查.
研究的目的:
- 为了探索COVID-19和腹膜内出血 (IPH) 之间的关联.
- 分析手术前和手术后的变化,死亡率和IPH患者的存活时间,包括COVID-19和没有COVID-19的患者.
主要方法:
- 82例手术治疗的IPH病例的回顾性分析 (2021年1月 - 2023年3月).
- 纳入标准:阳性COVID-19测试或无症状的过去感染.
- 通过脑CT/MRI确认诊断;从医院记录中收集的数据.
主要成果:
- 11% (9/82) 的患者检测出COVID-19阳性.
- 在COVID-19阳性和阴性组之间的死亡率没有显著差异 (p=0.651).
- 血瘤体积 (p < 0.001) 和中线转移 (p < 0.001) 的术后显著改善.
- 与阴性患者 (23天) 相比,COVID-19阳性患者的中位生存时间 (8天) 较短.
结论:
- 在IPH患者中,手术干预显著减少了血瘤体积和中线转移.
- COVID-19感染没有显著影响死亡率或大多数临床/实验室参数,除了AST和ALT水平.
- 在COVID-19阳性IPH患者中观察到减少生存时间的趋势.
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