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[中老年和老年中国男性的慢性疾病和可能的肉症之间的关联:前性队列研究]
Bo Liang1, Xue-Jun Shang2, Li-Jun Pei1
1Institute of Population Research / China Center for Population Health and Development, Peking University, Beijing 100871, China.
Zhonghua nan ke xue = National journal of andrology
|October 17, 2023
概括
诸如前列腺问题,认知障碍和抑郁症等慢性疾病显著增加了中国老年男性患可能的肉症的风险. 随着越来越多的同时存在的健康状况,风险会升级.
科学领域:
- 老年学是一门学科.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 标志着肌肉质量损失和肌肉衰弱的萨尔科佩尼亚是老年人群日益关注的问题.
- 慢性疾病在中年和老年人中越来越普遍,可能会影响身体功能.
研究的目的:
- 检查各种慢性疾病与可能的肉类的发病率之间的关联.
- 为了确定慢性疾病的数量是否影响45岁及以上的中国男性的肉症风险.
主要方法:
- 一项前性队列研究,利用中国健康与退休纵向研究 (CHARLS) 的数据.
- 在2011/2013年,从4878名男性 (年龄大于45岁) 获得的基线数据,没有可能的肉症,直到2015年进行了跟踪.
- 通过握力和五个坐姿测试来评估可能的肉类;用于分析的Cox比例风险模型.
主要成果:
- 前列腺疾病 (HR=1.16),认知障碍 (HR=1.23) 和抑郁症 (HR=1.12) 与可能增加的肉症风险有关.
- 随着慢性疾病的数量增加,风险增加:一个 (HR=1.22),两个 (HR=1.20),三个或更多 (HR=1.46).
- 在慢性疾病的数量和肉症风险 (P < 0.01) 之间观察到显著的剂量依赖关系.
结论:
- 前列腺疾病,认知障碍和抑郁症是中老年和老年中国男性可能发生的肉症的重要危险因素.
- 发展可能的肉症的风险表明,随着慢性并发症的数量增加,剂量取决于增加.
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