在八十多岁的人群中,氧化酸结石形成的驱动因素
Raymond Khargi1, Ryan M Blake2, Alan J Yaghoubian2
1Department of Urology, Icahn School of Medicine at Mount Sinai, New York, USA. Raymond.khargi2@mountsinai.org.
World journal of urology
|October 17, 2023
概括
患有氧酸结石的老年患者表现出独特的尿路特征,包括低酸盐和体积. 这一指南指导了有针对性的经验性治疗,当代谢测试是不可行的.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 代谢医学是一种代谢医学.
背景情况:
- 美国泌尿病学协会的指导方针建议对结石形成者进行代谢测试.
- 由于衰弱和社会障碍,对老年患者来说,代谢测试可能不切实际.
- 经验性治疗对于老年石头形成者至关重要,当代谢测试是不可行的.
研究的目的:
- 为了确定80岁的酸盐结石患者的独特的尿路代谢异常概况.
- 为老年人群指导更精确的经验性石头预防疗法.
主要方法:
- 从单个学术中心对患有氧酸盐结石的患者进行了回顾性分析.
- 根据年龄组对患者的分层 (≤40,41-59,60-79,≥80岁).
- 八旬期患者和其他年龄组之间的基线24小时尿液研究的比较,根据性别和功能障碍进行子组分析.
主要成果:
- 低酸性尿症,低尿液pH值和低尿量在老年患者中最常见,特别是八岁以上的患者.
- 超性尿症,超性尿症和超性尿症在年轻年龄组中更为普遍.
- 观察到尿路代谢特征的与年龄相关的差异.
结论:
- 随着年龄的增长,尿酸过低,尿液pH值低,尿液体积低的患病率更高.
- 伴随性疾病,如脏病,多药性和脱水,可能会导致这些与年龄相关的尿路形状.
- 针对水分,饮食 (水果/蔬菜) 和补充剂的经验性治疗是建议老年结石者不能接受代谢测试.
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