对热量刺激的主观和客观反应有助于将前体偏头痛与其他前体障碍区分开来
I P Hannigan1,2, S M Rosengren1,3, G K Bharathy4
1Central Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, 2006, Australia.
Journal of neurology
|October 17, 2023
概括
在热量测试期间的主观症状在前庭偏头痛 (VM) 患者明显高于其他头障碍. 结合主观和客观措施,可以更好地将VM与Meniere病 (MD) 的诊断分离.
科学领域:
- 神经科学是一个神经科学.
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 神经学 神经学
背景情况:
- 双热热量测试评估了水平前庭眼镜反射.
- 诱导症状通常被认为是不必要的副作用,而不是诊断信息.
研究的目的:
- 调查热量测试期间的主观症状和缓慢相速 (SPV) 在前体偏头痛 (VM) 患者中是否高于Meniere病 (MD) 和非前体 (NVD) 患者.
主要方法:
- 招募了1373名接受热量测试的患者.
- 评估了客观的阴囊 (SPV),主观的头 (SVS),主观的恶心 (SNS) 和测试完成.
- 与MD和NVD组的VM患者进行了比较.
主要成果:
- 主体 (SVS) 和恶心 (SNS) 在VM患者中明显高于非VM组 (p < 0.001).
- 在VM和非VM组之间没有观察到尼斯塔格姆斯SPV的显著差异.
- 结合热量数据和人口统计数据的机器学习模型在将VM与MD分离时实现了96%的灵敏度和85%的特异性.
结论:
- 热量测试中的主观评分是有意义的诊断措施,突出了VM的感知差异.
- 结合客观和主观的措施,特别是机器学习,增强了VM与MD的诊断分离.
相关概念视频
Equilibrium and Balance
4.7K
The inner ear assumes dual functionalities of auditory perception and equilibrium maintenance. The vestibule is the organ responsible for balance. This organ contains mechanoreceptors, specifically hair cells, endowed with stereocilia, which aid in deciphering information regarding the position and motion of our heads. Two intrinsic components, the utricle and saccule, help perceive head position, while the semicircular canals track head movement. Neurological messages initiated in the...
4.7K
The Vestibular System
39.6K
The vestibular system is a set of inner ear structures that provide a sense of balance and spatial orientation. This system is comprised of structures within the labyrinth of the inner ear, including the cochlea and two otolith organs—the utricle and saccule. The labyrinth also contains three semicircular canals—superior, posterior, and horizontal—that are oriented on different planes.
39.6K
Pathophysiology of Vomiting
510
Vomiting is a complex physiological response to expel harmful or irritating substances from the body. It's a defensive mechanism triggered by stimuli like poisons, microbial toxins, cytotoxic drugs, and mechanical abdominal distension. The process is centrally coordinated by the vomiting (or emetic) center located in the medulla of the brainstem. This area, rich in muscarinic M1, histamine H1, neurokinin 1 (NK1), and serotonin 5-HT3 receptors, coordinates the act of vomiting through...
510
Assessment of the Gastrointestinal System I: Subjective Data
202
Assessing the gastrointestinal (GI) system is a complex process that begins with collecting subjective data. This data, collected through patient interviews, provides crucial insights into the patient's health history, perception patterns, and lifestyle habits, all contributing significantly to GI health.
Health History
The initial step in assessing the GI system is obtaining a comprehensive health history. This includes inquiring about the patient's history or presence of problems...
Health History
The initial step in assessing the GI system is obtaining a comprehensive health history. This includes inquiring about the patient's history or presence of problems...
202


