对瘤病患者遵守常规疫苗接种计划的评估
David C Sabatino1, Peter Campbell1, Jennifer Santamala2
1Department of Pharmacy, NewYork-Presbyterian Hospital/Columbia University Medical Center, New York, NY, USA.
概括
癌症患者对疫苗的坚持率很低,只有1.4%的患者完全接种了疫苗. 这项研究强调了在瘤学人群中改善疫苗接种策略的必要性,以预防感染.
科学领域:
- 在瘤学瘤学.
- 预防传染病 预防传染病
- 公共卫生 公共卫生
背景情况:
- 癌症患者面临更高的感染风险.
- 疫苗对公共卫生至关重要,特别是在免疫力低下的人群中.
- 在美国一般成年人群中,低于最佳的疫苗坚持是普遍存在的.
研究的目的:
- 为了确定成年癌症患者的疫苗坚持率.
- 在瘤学人群中识别特定的疫苗坚持挑战.
主要方法:
- 对283名新诊断癌症的成年患者进行了回顾性队列研究.
- 对COVID-19 (SARS-CoV-2),流感,肺炎球菌,TDaP,RZV,HPV和乙型肝炎疫苗进行了评估.
- 主要结局:完全遵守疫苗.
主要成果:
- 仅在1.4%的瘤患者中观察到完全的坚持.
- 特定于疫苗的坚持:SARS-CoV-2 (38.9%),流感 (11.4%),肺炎球菌 (12.7%),TDaP (13.1%),RZV (3.5%),HPV (0%),乙型肝炎 (34%).
- SARS-CoV-2 疫苗接种率最高; 73% 接种至少一剂.
结论:
- 与普通人群相比,瘤学患者的疫苗坚持率较低.
- 医疗保健提供者和药剂师应该向患者提供关于疫苗的重要性的建议.
- 在化疗前和缓解后需要进行干预,以改善疫苗接种率.
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