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Updated: Jul 13, 2025

Studying Ribonucleotide Incorporation: Strand-specific Detection of Ribonucleotides in the Yeast Genome and Measuring Ribonucleotide-induced Mutagenesis
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Published on: July 26, 2018

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自发突变对酵母中高度重复的rDNA位置的定量和分子变异的贡献

Nathaniel P Sharp1, Denise R Smith1, Gregory Driscoll1

  • 1Department of Genetics, University of Wisconsin-Madison, Madison, Wisconsin, USA.

Genome biology and evolution
|October 17, 2023
PubMed
概括

酵母中的核糖体DNA (rDNA) 拷贝数是高度可变的. 突变积累揭示了自发突变可以破坏rDNA维护,导致拷贝数量下降,通过选择平衡.

关键词:
保持遗传变异的维持.突变的积累是突变的积累.结构变化的结构变化.

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