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有效的抗瘤免疫力可以通过向VISTA与TLR3-特定辅助剂结合,触发

Bo Wang1,2, Ziwei Ou1,2, Wenlong Zhong1,2

  • 1Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen (Zhongshan) University, Guangzhou, P.R. China.

Cancer immunology research
|October 17, 2023
PubMed
概括

膀癌中的高VISTA表达预示着生存率不佳. 用TLR3辅助剂向VISTA,通过重编程巨细胞和促进T细胞反应,减少瘤生长,显示出转化潜力.

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