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Updated: Jul 13, 2025

Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts
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Published on: December 22, 2015

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外体mRNA用于血管原生-骨质原生合骨修复

Yifan Ma1,2, Lili Sun3, Jingjing Zhang2

  • 1Department of Biomedical Engineering, The Ohio State University, Columbus, OH, 43210, USA.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|October 17, 2023
PubMed
概括

这项研究引入了带有生长因子mRNAs的治疗性小细胞外囊泡 (t-sEVs),并通过水凝传递,以增强骨再生. 这种新的方法为关键大小的骨缺陷提供了传统干细胞治疗的经济有效和更安全的替代方案.

关键词:
基化聚 (甘油脂酸盐) 烯酸盐 (PEGS-A) 水凝.骨形态遗传蛋白2 (BMP-2) 的mRNA与血管新生-骨质新生再生相结合.携带治疗性mRNA和相关的microRNA的小细胞外囊泡.基于膜的轨道蚀刻纳米电解 (TM-nanoEP) 技术血管内皮生长因子A (VEGF-A)

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