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不同皮肤电解方案在内源性疼痛调节中的有效性:双盲随机临床试验

Juan L Sánchez-González¹, Víctor Navarro-López², Laura Calderón-Díez¹

¹Department of Nursery and Physiotherapy, Faculty of Nursery and Physiotherapy, University of Salamanca, 37007, Salamanca, Spain.

Musculoskeletal science & practice

|October 17, 2023

概括

透皮电解 (PE) 可以增强疼痛调节通路,增加压力疼痛敏感性,减少时间总和与假药治疗相比. 强度没有显著影响本研究的结果.

科学领域:

疼痛研究疼痛研究
神经调节是一种神经调节.
临床试验方法论临床试验方法论

背景情况:

内源性疼痛机制 (EPM) 调节了痛感.
穿皮电解 (PE) 是一种用于治疗疼痛的技术.
调查PE对EPM的影响需要进行受控研究.

研究的目的:

为了确定皮电解 (PE) 是否增强内源性疼痛机制 (EPM).
为了比较不同强度的PE与假干预的效果.
评估疼痛敏感度和调制的变化.

主要方法:

随机临床试验,包括46名无症状受试者.
三组:假装,低强度PE (0.3 mA) 和高强度PE (3 mA).
超声波导向PE应用于侧面表皮;双边评估结果.

主要成果:

高强度PE显著增加了侧面表皮节的压力疼痛值 (PPT),而不是假的.
低强度和高强度PE都显著降低了右前部的时间总和 (TS).
在不同组的条件疼痛调制 (CPM) 中没有观察到显著的变化.

结论:

一次PE会话可以调节疼痛路径,影响压力疼痛敏感性和时间总和.
观察到PE对疼痛调节的影响,即使是逆侧.
在低强度和高强度PE之间没有发现显著的结果差异.

关键词:

电解通过皮肤通过皮肤.内生性疼痛是一种内生性疼痛.疼痛疼痛疼痛疼痛随机对照试验是随机对照试验.

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