动脉旋转标记MRI使用螺旋采集和并发场监测
1Institute for Biomedical Engineering, University and ETH Zürich, Zürich, Switzerland; Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, University of Zurich, Switzerland.
Journal of magnetic resonance (San Diego, Calif. : 1997)
|October 17, 2023
概括
这项研究引入了一种使用螺旋成像进行动脉脊柱标记MRI (ASL-MRI) 的新方法. 该技术显著减少了文物并提高了图像质量,提供了更快,更强大的 perfusion 成像.
科学领域:
- 磁共振成像 (MRI) 是一种磁共振成像技术.
- 医学物理 医学物理
- 神经成像是一种神经成像.
背景情况:
- 动脉旋转标记 (ASL) MRI对于测量大脑输液至关重要,但其信号噪声比 (SNR) 较低.
- 更短的回声时间 (TE) 改善ASL SNR,螺旋轨迹提供更快的获取和更短的TE.
- 然而,螺旋ASL容易受到来自磁场不均质和梯度不完美的磁场工件的影响.
研究的目的:
- 开发一种强大的螺旋ASL成像技术,克服固有的局限性.
- 改进信号噪声比 (SNR) 并减少ASL图像中的工件.
- 为了实现更快,更具运动强度的 perfusion 成像.
主要方法:
- 实现了单射和多射螺旋ASL采集.
- 使用了一个全面的信号模型,考虑静态偏振,线圈灵敏度,动态B0和梯度场变化 (高达三级).
- 使用3级动态现场摄像机与NMR现场探测器同时监测螺旋ASL采集.
主要成果:
- 在3mm和2mm内平面分辨率重建的ASL图像显示明显减少模糊,别名和扭曲.
- 该方法有效地弥补了静态偏振和动态场波动.
- 同时的现场监测允许对准静态B0漂移进行校正,确保一致的编码几何.
结论:
- 在螺旋式ASL获取中同时进行现场监控,有效地减轻了螺旋轨迹的传统漏洞.
- 这种方法产生了高质量的ASL图像,增强了SNR,速度和运动稳定性.
- 开发的技术提升了螺旋ASL在 perfusion成像中的实用性.
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