慢性精神分裂症临床症状与alexithymia之间的关联性性别差异:基于中国汉族人口的大型样本研究
ZhaoXuan Shang1, ChunQing Fang1, XiaoE Lang2
1Department of Psychology and Cognitive Science, East China Normal University, Shanghai, China.
Journal of affective disorders
|October 17, 2023
概括
精神分裂症患者的alexithymia患病率显示没有性别差异. 在两种性别中,负面症状与alexithymia有关,而认知症状影响男性,抑郁症状影响女性.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 社会认知是指社会认知.
背景情况:
- 亚历克西西米亚是精神分裂症中常见的社会认知缺陷.
- 关于alexithymia与精神分裂症症状和性别差异的联系的先前研究是不一致的.
- 在中国精神分裂症患者中对亚历克西西米亚的性别差异的大规模研究是有限的.
研究的目的:
- 研究亚历克西西米亚患病率的性别差异及其与慢性精神分裂症中汉族患者临床症状的关系.
- 在男性和女性精神分裂症患者中探索alexithymia和特定症状集群 (积极,消极,认知,抑郁) 之间的相关性.
主要方法:
- 一项针对987名被诊断患有慢性精神分裂症的汉族患者的大规模调查.
- 使用阳性和阴性综合征量表 (PANSS) 评估临床症状.
- 使用多伦多alexithymia尺度 (TAS-20) 对自我报告的alexithymia的评估.
主要成果:
- 在男性 (35.51%) 和女性 (26.91%) 精神分裂症患者中,alexithymia的患病率没有显著差异.
- 阳性和阴性综合征量表 (PANSS) 和多伦多亚历克西西米亚量表 (TAS-20) 的得分在两种性别中都有广泛的相关性.
- 多重回归显示,TAS总得分与男性的负面和认知症状以及女性的负面和抑郁症状正相关.
结论:
- 性别似乎没有影响慢性精神分裂症中alexithymia的患病率.
- 在男性和女性患者中,负面症状与alexithymia相关.
- 认知症状在男性中与alexithymia有独特的联系,而抑郁症状在女性中与alexithymia有独特的联系.
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