在临床评估IIb等级mopox病变的变化
Benjamin Jones1, Amy Paterson1, Naseem AlKhoury1
1Pandemic Sciences Institute, University of Oxford, Oxford, United Kingdom.
概括
评估mopox病变是一个挑战. 这项研究发现,临床医生在评估mopox病变时具有中等的可靠性和一致性,这突显了对标准化分类系统的需求.
科学领域:
- 传染性疾病 传染性疾病
- 皮肤病学 皮肤病学
- 公共卫生 公共卫生
背景情况:
- 麻疹病毒 (molluscum contagiosum virus) 的爆发在损伤评估方面带来了挑战.
- 准确的病变分类对于临床试验和患者管理至关重要.
研究的目的:
- 评估临床医生中mopox损伤评估的评价者间可靠性和一致性.
- 为了确定分类mopox病变的一致性,将其分为活跃的,状的,已解决的或无法分类的类别.
主要方法:
- 一项调查对53名临床医生进行了调查,他们对mpox有经验.
- 临床医生对20张mopox病变图像进行了分类.
- 评估者之间的可靠性是使用Fleiss' kappa进行评估的,一致性是通过准确一致性的比例来衡量的.
主要成果:
- 观察到中等级别之间的可靠性,Fleiss' kappa系数为0.417.
- 在临床医生中确切同意的比例为61%.
- 临床医生在评估mopox病变时报告了7/10的中位信心评分.
结论:
- 对mopox病变的临床评估显示了中等可靠性和一致性.
- 临床护理和公共卫生决策需要标准化的损伤分类系统.
- 临床试验的替代终点可能是必要的.
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