深度分子跟踪超过12年发展的子宫内膜癌从单一患者的增生在一个单一的病人

Katherine Reid1, Olga Camacho-Vanegas2, Deep Pandya3

  • 1Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA; katherine.reid@mssm.edu.

概括

这项研究跟踪了一个患者12年内子宫内膜癌 (EndoCA) 的发展,识别了关键的遗传突变. 孕激素治疗显著降低了导致癌症的PTEN突变水平,为非手术EndoCA管理提供了洞察力.

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