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Updated: Jun 25, 2026

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新型喷涂热敏胺基凝用于局部应用:开发,表征和体外生物活动

Muhammet Davut Arpa1, Ebrar Elif Kesmen2, Sevde Nur Biltekin3,4

  • 1Department of Pharmaceutical Technology, School of Pharmacy, Istanbul Medipol University, 34815, Istanbul, Turkey. mdarpa@medipol.edu.tr.

AAPS PharmSciTech
|October 17, 2023
PubMed
概括

含有胺 (BZD) 的新可喷的热敏水凝可以改善局部疼痛缓解. 这些配方增强了皮肤粘附和抗炎作用,为传统凝提供了方便的替代品.

关键词:
在HPMC中,HPMC是指HPMC.基胺的使用情况在位凝在位凝波洛克萨默斯 (Poloxamer) 是一个波洛克萨默斯 (Poloxamer) 公司.热敏水凝是一种热敏水凝.

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Stimuli-activated drug delivery systems are designed to release drugs in response to specific physical, chemical, or biological stimuli. These systems often utilize hydrogels—three-dimensional, hydrophilic polymer networks capable of swelling in aqueous environments and retaining significant fluid volumes. Upon exposure to particular stimuli, these hydrogels undergo structural transitions that allow the embedded drug to be released. Due to this adaptive behavior, such systems are also called...