在一个带有两个脉动动脉的手腕幻影中进行生物阻抗分析的调查
Yang Yu1, Andrew Lowe2, Gautam Anand2
1Institute of Biomedical Technologies, Auckland University of Technology, Auckland, 1010, New Zealand. yyu@aut.ac.nz.
Cardiovascular engineering and technology
|October 17, 2023
概括
这项研究表明,关动脉显著影响来自手腕辐射动脉的生物阻抗分析 (BIA) 信号. 幻影实验证实BIA测量捕获来自两个动脉的脉动信息.
科学领域:
- 生物医学工程 生物医学工程
- 生理测量生理测量
背景情况:
- 生物阻抗分析 (BIA) 被探索用于血液动力学监测.
- 现有的BIA模型往往忽略了手腕/前臂多个动脉的联合脉动效应.
- 了解这些相互作用对于准确的生理评估至关重要.
研究的目的:
- 研究和量化两个同步脉动动脉 (辐射动脉和动脉) 对远端前臂BIA测量的影响.
- 为了建模影响BIA信号的复杂血动力学相互作用.
- 为改进基于BIA的监测提供基础见解.
主要方法:
- 使用有限元法 (FEM) 模拟了一个3D手腕段,其中有两个脉动动脉.
- 一个有两个动脉的人工手腕幻象是使用凝组织和盐水血幻象构建的.
- 使用多频阻抗分析仪 (MFIA) 测量阻抗信号,同时动脉被收缩.
主要成果:
- 模拟和实验都证实了关动脉对放射性动脉BIA信号的显著,不可忽视的影响.
- 在幻影实验中观察到的阻力变化表明,BIA信号整合了来自两个动脉的脉动信息.
- 单个动脉阻力变化的总和接近了综合效应,验证了这些发现.
结论:
- 这项研究介绍了第一个模拟和幻影研究,对两个同步脉动动脉在远端前臂BIA下进行模拟和幻影研究.
- 这些发现提高了对多动脉区域测量阻抗信号形态的理解.
- 结果表明电极配置策略用于单个或多个动脉传感,并为未来的无袖血压测量 (BPM) 开发提供信息.
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