塑性支气管炎与呼吸道共囊病毒感染相关:一个病例报告
Wei Wang1, Lei Zhang1, Wei-Ke Ma1
1Shenzhen Children's Hospital, No. 7019, Yitian Road, Futian District, Shenzhen, 518026, Guangdong, China.
BMC pediatrics
|October 17, 2023
概括
呼吸道综合体病毒 (RSV) 可能导致免疫功能低下儿童的塑性支气管炎 (PB). 早期支气管镜检查对于诊断和治疗严重病例的诊断和治疗至关重要,这些病例对通风或ECMO无反应.
科学领域:
- 儿科肺病学 儿科肺病学
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
背景情况:
- 塑性支气管炎 (PB) 的确切原因尚不清楚.
- 与PB相关的肺部感染正在增加,但很少有人报告呼吸道同胞病毒 (RSV) 是病因.
研究的目的:
- 报告一个罕见的塑性支气管炎 (PB) 病例,该病例发生在免疫受损儿童身上.
- 突出RSV在PB病因学中的潜在作用.
- 强调在严重呼吸衰竭中及时进行支气管镜检查的重要性.
主要方法:
- 一个2岁免疫力低下的女孩的病例报告,患有严重的呼吸困扰.
- 诊断程序包括支气管镜检查,分泌物病理学和膜洗液下一代测序 (NGS).
- 治疗包括机械通风,ECMO和支气管镜去除塑料分泌物.
主要成果:
- 该患者被诊断为I型PB,RSV通过NGS被确定为唯一的病原体.
- 支气管镜干预改善了呼吸不良,导致在高流量鼻腔管上排出液.
- 患者后来出现了支气管炎消灭症的后续症状.
结论:
- RSV是PB的潜在原因,特别是在免疫力低下的儿童中.
- 在患有肺部感染和耐火性低氧症的患者中,尽管有机械通风或ECMO,但应该怀疑PB.
- 及时进行支气管镜检查对于诊断和管理PB至关重要.
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