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Updated: Jul 13, 2025

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基于连接体和结构的层次虚拟查级联寻找新型表皮生长因子受体抑制剂

Donghui Huo1,2, Zhiqi Sun1, Maolin Wang3,4

  • 1State Key Laboratory of Chemical Resource Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, China.

Chemical biology & drug design
|October 18, 2023
PubMed
概括

研究人员通过虚拟查确定了新的表皮生长因子受体 (EGFR) 抑制剂. 生物测试证实了13种活性化合物,其中3种具有强烈的抑制活性,指导未来的癌症药物设计.

关键词:
皮肤上生长因子受体抑制剂分子聚类是分子聚类.分子对接的分子对接.虚拟选是虚拟的选.

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