对产后抑郁症的全基因组协会研究的元分析

Jerry Guintivano¹, Enda M Byrne¹, Jacqueline Kiewa¹+76

• ¹Department of Psychiatry (Guintivano, Bauer, Watson, Krohn, Rubinow, Meltzer-Brody, Sullivan), Department of Genetics (Raffield, Li, Sullivan), and Department of Biostatistics (Li), University of North Carolina at Chapel Hill; Child Health Research Centre (Byrne, Kiewa), Institute for Molecular Bioscience (Byrne, Walker), Frazer Institute (Olsen), School of Public Health (Whiteman), and Queensland Brain Institute (Wray), University of Queensland, Brisbane, Australia; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm (Yao, Lu, Xiong, Viktorin, Sullivan); Center for Biomarker Research and Precision Medicine, Virginia Commonwealth University, Richmond (Aberg, van den Oord); Division of Psychiatry (Adams, McIntosh), Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer (A. Campbell), and Usher Institute for Population Health Sciences and Informatics (A. Campbell), University of Edinburgh, Edinburgh; MRC Genomic and Precision Medicine Research Unit, Division of Human Genetics, Institute for Infectious Diseases and Molecular Medicine (M.L. Campbell), SAMRC Unit on Risk and Resilience in Mental Disorders, Department of Psychiatry, and Neuroscience Institute (Koen, Stein), and Department of Paediatrics and Child Health and MRC Unit on Child and Adolescent Health (Zar), University of Cape Town, Cape Town, South Africa; Global Initiative for Neuropsychiatric Genetics Education in Research (M.L. Campbell) and Stanley Center for Psychiatric Research (Sealock), Broad Institute, Cambridge, Mass.; Center for Precision Psychiatry, Department of Psychiatry (Choi, Feng, Smoller), Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine (Choi, Feng, Smoller), and Analytic and Translational Genetics Unit (Sealock), Massachusetts General Hospital, Boston; Department of Psychiatry, Harvard Medical School, Boston (Choi, Feng, Smoller); Department of Mental Disorders (Corfield, Reichborn-Kjennerud, Tesli) and Center for Genetic Epidemiology and Mental Health (Havdahl), Norwegian Institute of Public Health, Oslo; Nic Waals Institute, Lovisenberg Diaconal Hospital, Oslo (Corfield, Havdahl); Department of Psychology, PROMENTA Research Center (Havdahl), NORMENT Center (Andreassen), K.G. Jebsen Center for Neurodevelopmental Disorders (Andreassen, Westlye), Institute of Clinical Medicine (Reichborn-Kjennerud), and Department of Psychology (Westlye), University of Oslo, Oslo; Department of Medicine (Hucks, Davis), Division of Genetic Medicine (Hucks, Davis), and Vanderbilt Genetics Institute (Hucks), Vanderbilt University Medical Center, Nashville; National Center for Register-Based Research (Mægbæk, Munk-Olsen) and Department of Economics and Business Economics (Mægbæk), Aarhus University, Aarhus, Denmark; Department of Epidemiology, Biostatistics, and Clinical Research, AP-HP Nord-Université Paris Cité, Paris (Mullaert); UMR 1137 IAME, INSERM, Paris (Mullaert); Department of Psychiatry and Behavioral Sciences (Peterson), Institute for Genomics in Health (Peterson), and Department of Psychiatry and Behavioral Sciences (Bigdeli), SUNY Downstate Health Sciences University, Brooklyn; Centre for Academic Mental Health, Population Health Sciences, Bristol Medical School, and MRC Integrative Epidemiology Unit, University of Bristol, Bristol, U.K. (Sallis); Discipline of Psychology, Curtin University, Perth, Australia (Watson); Division of Paediatrics, University of Western Australia, Perth (Watson); Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, U.K. (Yang, Anney, Hubbard, I. Jones, Pardiñas, Di Florio); Psychological Medicine, University of Worcester, Worcester, U.K. (Gordon-Smith, L.A. Jones, Perry); Department of Psychiatry, Catharina Hospital, Eindhoven, the Netherlands (Mihaescu); Department of Health Science and Technology, Aalborg University, Aalborg, Denmark (Nyegaard); Department of Clinical Sciences, Sulaiman AlRajhi University, Bukairiyah, Saudi Arabia (Saquib); Department of Epidemiology, Herbert Wertheim School of Public Health and Human Longevity Science, University of California, San Diego, La Jolla (Shadyab); Division of Mental Health and Addiction (Andreassen), Center for Research and Education in Forensic Psychiatry, Department of Mental Health and Addiction (Tesli), and NORMENT, Division for Mental Health and Addiction (Westlye), Oslo University Hospital, Oslo; Research Service, VA New York Harbor Healthcare System, New York (Bigdeli); Lawrence S. Bloomberg Faculty of Nursing, University of Toronto, Toronto (Dennis); INSERM U1266, Université de Paris, Paris (Dubertret); Department of Psychiatry, AP-HP, Louis Mourier Hospital, Colombes, France (Dubertret, Tebeka); Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario (Frey, Van Lieshout); Women's Health Concerns Clinic, St. Joseph's Healthcare Hamilton, Hamilton, Canada (Frey); Department of Psychiatry, Sunnybrook Health Science Centre and Research Institute, Toronto (Grigoriadis); Department of Psychiatry, University of Toronto, Toronto (Grigoriadis, Kennedy, Vigod); Hôpital Bichat, Department of Epidemiology, Biostatistics, and Clinical Research, AP-HP, Paris (Gloaguen); Molecular Brain Science Department, Centre for Addiction and Mental Health, Toronto (Kennedy); Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden (Kunovac Kallak, Skalkidou); Genetic Epidemiology (Martin) and Population Health Program (Olsen, Whiteman), QIMR Berghofer Medical Research Institute, Brisbane, Australia; Parent-Infant Research Institute, Heidelberg Heights, Australia (Milgrom); University of Melbourne, Melbourne, Australia (Milgrom); Department of Clinical Research, Psychiatric Research Unit, University of Southern Denmark, Odense (Munk-Olsen); BC Children's Hospital, Vancouver (Oberlander); Department of Pediatrics, Faculty of Medicine, University of British Columbia, Vancouver (Oberlander); Université Paris Cité, Institute of Psychiatry and Neuroscience of Paris (IPNP), INSERM UMR1266, Team "Genetic vulnerability to addictive and psychiatric disorders," Paris (Ramoz); GHU Paris Psychiatrie et Neurosciences, CMME, Hôpital Sainte-Anne, Paris (Ramoz); Behavioral Sciences and Social Medicine, Florida State University, Daytona Beach (Robertson Blackmore); Department of Psychiatry, University of Wisconsin, Madison (Stowe); Department of Psychiatry, University of Calgary, Calgary, Canada (Taylor); INSERM U1266, Université Paris Cité, Paris (Tebeka); Department of Psychiatry, Women's College Hospital, Toronto (Vigod); Institute of Biological Psychiatry, Mental Health Services, Copenhagen University Hospital, Copenhagen (Werge); Department of Clinical Medicine and LF Center for Geogenetics, Globe Institute, University of Copenhagen, Copenhagen (Werge); iPSYCH, Lundbeck Foundation Initiative for Integrative Psychiatric Research, Copenhagen (Werge).