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Updated: Jul 13, 2025

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释放作为选择性LH2抑制剂的1,3-二开类型的潜力

Juhoon Lee1,2, Hou-Fu Guo3, Shike Wang4

  • 1Division of Chemical Biology and Medicinal Chemistry, College of Pharmacy, University of Texas at Austin, Austin, Texas 78712, United States.

ACS medicinal chemistry letters
|October 18, 2023
PubMed
概括

新的化合物抑制了lysyl氧酶2 (LH2),一种促进肺癌转移的酶. 这些抑制剂通过向特定的原交叉链路来减少癌细胞迁移,为肺癌提供了潜在的治疗策略.

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