在有意识障碍的患者中,长期消毒的预测因素
Ying Chen1, Gulijiakela Aishan1, Shunjuan Fan1
1Department of Rehabilitation Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Frontiers in neurology
|October 18, 2023
概括
在患有意识障碍 (DOC) 的患者中预测气管管切除术断管是至关重要的. 阴性修饰埃文斯蓝色染料测试 (MEBDT) 和更高的意识水平是DOC患者成功脱的关键预测因素.
科学领域:
- 神经学 神经学
- 关键护理医学 关键护理医学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 在有意识障碍 (DOC) 的患者中,气管管切除术的预后仍然具有挑战性,原因是不完全理解的预测因素.
- 确定可靠的指标来确定脱是改善患者管理和结果的关键.
研究的目的:
- 在有意识障碍 (DOC) 的患者中识别气管切除术脱管的预测因子.
- 评估修改埃文斯蓝色染色试验 (MEBDT) 的可行性和安全性,用于气管切除DOC患者.
主要方法:
- 在2016年1月至2022年9月期间入院的141名气管切除术DOC患者的回顾性研究.
- 收集的数据包括人口统计,意识水平 (GCS,CRS-R,UWS/MCS),MEBDT结果,mRS和FOIS.
- 考克斯回归和卡普兰-梅尔分析被用来调查脱的预测因素.
主要成果:
- 在61%的患者中,成功的脱发生.
- 较高的意识水平 (MCS与UWS) 和负的MEBDT结果与成功的脱显著相关 (多变量分析:HR=6.694和HR=1.873).
- 卡普兰-梅尔分析显示,MEBDT阴性患者和MCS患者在12个月内脱的概率更高.
结论:
- 阴性MEBDT结果是DOC患者气管切除术成功的重要预测因素.
- 较高的意识水平,特别是最小意识状态 (MCS),与更高的脱的可能性有关.
- 这些发现有助于预测脱管治疗的结果,并优化护理的气管切开DOC患者.
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