植物生物系统设计研究路线图1.0
Xiaohan Yang1,2, June I Medford3, Kasey Markel4
1Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA.
Biodesign research
|October 18, 2023
概括
植物生物系统的设计提供了创新的策略,以提高作物产量和质量,解决全球需求. 这种方法使用预测模型和先进的技术,如基因组编辑,以加速植物遗传改进和创建新系统.
科学领域:
- 植物科学 植物科学
- 合成生物学 合成生物学
- 生物工程是生物工程.
背景情况:
- 人类的生存和福祉从根本上取决于植物的基本资源,如食物,材料和能源.
- 目前的植物遗传改进方法,包括育种和有限的基因工程,不足以满足日益增长的全球数量和质量的需求.
研究的目的:
- 提出植物生物系统设计的全面路线图,概述理论,原则和方法.
- 探索植物生物系统设计在基础和应用植物生物学中的潜在应用.
- 确定挑战,机遇和优先事项,以推进这个跨学科领域.
主要方法:
- 利用生物系统的预测模型进行创新的植物科学研究.
- 采用基因组编辑和遗传电路工程来加速植物遗传改进.
- 探索植物基因组的新合成,以创造新的植物系统.
主要成果:
- 植物生物系统的设计代表了从试错转向基于模型的预测策略的范式转变.
- 这种方法促进了快速的遗传改进,并创造了全新的植物功能.
- 提供了一份路线图,详细说明理论框架,技术方法和应用潜力.
结论:
- 植物生物系统的设计对于应对粮食安全和可持续性的全球挑战至关重要.
- 国际合作和关注社会责任对于公众的接受和这一领域的进步至关重要.
- 未来的研究应该优先发展强大的生物系统设计框架,并促进公众的信任.
相关概念视频
Introduction to Plant Diversity
From Water to Land
Plant Breeding and Biotechnology
Crop cultivation has a long history in human civilization, with records showing the cultivation of cereal plants beginning at around 8000 BC. This early plant breeding was developed primarily to provide a steady supply of food.
Synthetic Biology
Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...
Golden rice
Golden rice is a genetically modified...
Bioreactor Design and Operational System
Bioreactors are engineered vessels designed to cultivate microorganisms under controlled conditions for industrial bioprocessing. They maintain sterility and allow precise regulation of pH, temperature, oxygen, and nutrient levels to optimize microbial growth and metabolite production. Bioreactors range from small laboratory units of 1 liter to industrial systems holding up to 500,000 liters, though only about 75% of their volume is actively used for fermentation. The remaining headspace...
Production of Biopesticides
Biopesticides offer a sustainable alternative to chemical pesticides, utilizing microbial agents to control agricultural pests. Bacillus thuringiensis (Bt) is a widely employed bacterium known for its potent insecticidal activity. Bt biopesticides are favored for their specificity to insect pests, minimal environmental impact, and natural degradability.Mechanism of Bt Toxin Action Bt produces insecticidal crystal (Cry) proteins during its sporulation phase. These proteins form parasporal...


