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马来西亚青少年功能变化及其决定因素
Fathhullah Azmie Nawawi1,2, Wan Ahmad Hafiz Wan Md Adnan3, Maslinor Ismail1
1Department of Social and Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Kidney international reports
|October 18, 2023
概括
青少年的功能随着时间的推移而下降,功能下降的患病率显著增加. 早期发现和预防年轻人患慢性病 (CKD) 的危险因素对长期健康至关重要.
科学领域:
- 青少年健康 青少年健康
- 腎臟病學 (nephrology) 是一種醫學專業.
- 公共卫生 公共卫生
背景情况:
- 青少年的健康和福祉,特别是慢性病 (CKD),往往被忽视.
- 早期发现青少年的功能障碍对于及时干预至关重要.
研究的目的:
- 为了研究青少年的功能变化.
- 分析非传染性疾病 (NCD) 风险因素与青少年功能之间的纵向关系.
主要方法:
- 前性队列研究 (马来西亚健康和青少年纵向研究小组 - MyHeART) 涉及607名青少年 (年龄13-17岁).
- 通过使用施瓦茨方程在三个时间点 (2012,2014,2016) 计算的估计质过率 (eGFR) 评估功能.
- 概括估计方程 (GEE) 用于分析eGFR和NCD风险因素之间的纵向关联.
主要成果:
- 降低EGFR (60-89毫升/分钟/1.73米2) 的患病率从6.1% (2012) 增加到40.2% (2016).
- 青少年的eGFR表现出纵向下降,特别是在青春期初至中期.
- 较低的eGFR与男性性别,农村居住,病态肥胖和潜在的蛋白质消费有关.
结论:
- 功能变化可以在青春期检测到,并且与多种非传染性疾病的风险因素有关.
- 需要全面的预防策略来解决青少年CKD和相关的健康问题.
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