三维剪切波弹性图使用2D行列定位 (RCA) 阵列
Zhijie Dong1,2, Jihun Kim1,2,3, Chengwu Huang4
1Beckman Institute for Advanced Science and Technology, University of Illinois Urbana-Champaign, Urbana, IL, USA.
BME frontiers
|October 18, 2023
概括
一种新的3D剪波弹性图 (SWE) 技术使用2D行列定位 (RCA) 阵列进行高体积率成像. 这种方法可以进行可靠的3D组织硬度评估,为临床转化铺平了道路.
科学领域:
- 超声波成像 超声波成像
- 生物医学工程 生物医学工程
- 医学物理 医学物理
背景情况:
- 剪波弹性图 (SWE) 量化了组织度,这对于诊断癌症和肝纤维化等疾病至关重要.
- 目前的SWE技术仅限于2D,因为高体积率3D成像的挑战.
- 3D成像对于准确评估异质组织特性至关重要.
研究的目的:
- 开发一种使用二维行列定位 (RCA) 阵列的新型3D剪切波弹性图 (SWE) 技术.
- 为了使3D SWE使用外部振动或声辐射力 (ARF) 作为剪切波源.
- 提供低成本,高容量率的解决方案,与现有的临床超声波系统兼容.
主要方法:
- 开发了一种3D SWE方法,采用2D RCA阵列,达到高达2000Hz的音量率.
- 使用模仿组织弹性幻象来评估该技术的性能.
- 在体内验证通过一个案例研究进行.
主要成果:
- 成功检测了由外部振动和ARF引起的3D剪切波运动.
- 对幻影和体内数据进行强大的3D剪切波速度图的重建.
- 展示高体积率的3D成像能力.
结论:
- 使用2D RCA阵列开发的3D SWE技术为体积组织硬度评估提供了一个实用的解决方案.
- 该方法支持3D SWE的临床翻译,提供了一个具有成本效益和高容量率的替代方案.
- 这一进步解决了二维SWE的局限性,并促进了全面的组织评估.
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