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Updated: Jul 13, 2025

qKAT: Quantitative Semi-automated Typing of Killer-cell Immunoglobulin-like Receptor Genes
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HLA-DPB1*13:01与增强的相关,KIR2DS4*001与减少的保护,防止发生严重的COVID-19发展

Ticiana D J Farias1,2, Silvia Brugiapaglia3, Susanna Croci4,5

  • 1Department of Biomedical Informatics, University of Colorado School of Medicine, Aurora, Colorado, USA.

HLA
|October 18, 2023
PubMed
概括

人类白细胞抗原 (HLA) 和杀手细胞免疫球蛋白类受体 (KIR) 的遗传变异影响COVID-19的严重程度. 特定的HLA和KIR全型与疾病结果有关,影响了先天性和适应性免疫力.

关键词:
在 COVID-19 疫情中,在HLAII类中,HLA是II类.这就是HLA-DPB1的原因.的IFN-α抗体.这就是KIR2DS4DS4的原因.

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