流行病学调查揭示了TAMV从虫传播到宿主的风险
Abulimiti Moming1, Yuan Bai1, Shengyao Chen1
1State Key Laboratory of Virology and National Virus Resource Center, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
Infectious diseases (London, England)
|October 18, 2023
概括
坦迪病毒 (TAMV) 在中国新疆流传,由亚洲和皮肤病原虫 (Dermacentor nuttalli) 传播. 这种由传播的病毒对公众健康构成风险,至少自2006年以来,它在动物身上存在的证据证明了这一点.
科学领域:
- 兽医病毒学 兽医病毒学
- 动物传染病研究研究
- 公共卫生昆虫学 昆虫学
背景情况:
- 传播的病毒性疾病是越来越严重的公共卫生问题.
- 坦迪病毒 (TAMV) 是一种Orthonairovirus,被怀疑会导致人类发烧性疾病,但其流行病学和溢出风险尚不清楚.
研究的目的:
- 调查在中国新疆的和动物种群中TAMV的存在和流行情况.
- 为了确定主要负责TAMV传播的载体.
- 评估TAMV在动物中的血清流行,以了解其循环和潜在的动物传播风险.
主要方法:
- 来自新疆的池被测试TAMVRNA使用RT-PCR测试.
- 血清流行率通过免疫光测试,西部涂抹和路西法酶免疫沉系统 (LIPS) 测试来确定.
- 对检测到的TAMV菌株进行了植物遗传学分析.
主要成果:
- 在4.7%的池中检测到TAMVRNA,其中Hyalomma asiaticum和Dermacentor nuttalli被确定为关键载体.
- 新疆的TAMV菌株与国际菌株有着密切的遗传关系.
- 在1.1%的受访动物中发现了TAMV抗体,这表明至少自2006年以来一直在循环,在绵羊,狗和动物中显著的阳性.
结论:
- 通过TAMV传染给各种动物物种,存在很大的动物感染风险.
- 由于TAMV及其载体的广泛分布,需要采取准备和控制策略.
- 持续警对于管理像TAMV.这样的新出现的传播动物传染病至关重要.
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