对染色质景观和RNA聚合酶II对SIN3调节基因的结合分析

Imad Soukar1, Anindita Mitra1, Lori A Pile1

  • 1Department of Biological Sciences, Wayne State University, Detroit, MI 48202, USA.

Biology open
|October 18, 2023
PubMed
概括

基因素SIN3修饰复杂异型SIN3 220和SIN3 187通过改变染色质结构和RNA聚合酶II结合来调节基因表达. 这项研究揭示了与SIN3介导的基因抑制相关的特定的基因素修饰和暂停的聚合酶动态.

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