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相关概念视频

Allergic Reactions02:06

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Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
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Proteins are broken down into amino acids during digestion. Unlike fats and carbohydrates, which are stored for later use, proteins are not. Instead, amino acids are either used to produce ATP through oxidation or contribute to the creation of new proteins for the growth and repair of the body. Any surplus amino acids from the diet are converted into glucose or triglycerides rather than excreted.
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Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
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Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
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Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE
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牛奶蛋白质过敏 牛奶蛋白质过敏

Rohan Malik1, Sanjeevani Kaul2

  • 1Division of Pediatric Gastroenterology, Hepatology and Clinical Nutrition, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India. dr.rohanmalik@gmail.com.

Indian journal of pediatrics
|October 18, 2023
PubMed
概括

牛奶过敏是一种常见的婴儿疾病,涉及对牛奶蛋白质的反应. 诊断涉及消除饮食和挑战,管理侧重于避免过敏原和专用配方.

关键词:
慢性腹 慢性腹 慢性腹牛奶蛋白质过敏 牛奶蛋白质过敏食物蛋白质过敏 食物蛋白质过敏与食物蛋白相关的过敏性肠道炎 (FPAP)食物蛋白引起的肠球炎综合征 (FPIES)食物蛋白引起的肠病 (FPE)

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科学领域:

  • 过敏和免疫学 过敏和免疫学
  • 儿科 儿科 儿科
  • 胃肠病学 胃肠病学

背景情况:

  • 牛奶过敏 (CMA) 是婴儿中普遍存在的食物过敏,影响0.5%至3%.
  • 反应可以是IgE介导的,非IgE介导的,或混合的,呈现不同的症状.
  • 胃肠道问题,如肠道病变和逆流是常见的,特别是在非IgE CMA.

研究的目的:

  • 为了提供关于牛奶过敏的全面概述.
  • 讨论诊断方法和管理策略.
  • 突出目前对预防和新兴治疗方法的理解.

主要方法:

  • 审查关于牛奶过敏诊断和管理的现有文献.
  • 讨论诊断工具,包括口腔挑战和免疫测试.
  • 分析治疗干预措施,如消除饮食和专用配方.

主要成果:

  • 双盲安慰剂控制的口服挑战是诊断的黄金标准.
  • 消除饮食,然后监督挑战是常见的诊断实践.
  • 过敏原的消除导致症状的缓解;广泛化或氨基酸配方是推的替代品.

结论:

  • 牛奶过敏需要仔细的诊断和管理,主要是通过避免过敏原.
  • 耐受性随着时间的推移而发展,需要定期重新引入试验.
  • 口服免疫疗法是IgE介导CMA的新兴治疗方法,而母乳养和及时补充养可能有助于预防.