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Updated: Jul 13, 2025

Manufacturing Chimeric Antigen Receptor CAR T Cells for Adoptive Immunotherapy
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Manufacturing Chimeric Antigen Receptor CAR T Cells for Adoptive Immunotherapy

Published on: December 17, 2019

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在B-ALL患者中,CAR-T细胞的功能多样化和动态

Zongcheng Li1, Lei Zhao2, Yuanyuan Zhang2

  • 1State Key Laboratory of Experimental Hematology, Haihe Laboratory of Cell Ecosystem, Institute of Hematology, Senior Department of Hematology, Fifth Medical Center of Chinese PLA General Hospital, Beijing 100071, China.

Cell reports
|October 18, 2023
PubMed
概括

这项研究绘制了白血病患者输液后的仿制抗原受体 (CAR) -T细胞进化图. 细胞毒性CAR-T细胞占主导地位与缓解相关,而与B细胞相似的CAR-T细胞可以预测复发.

关键词:
B细胞急性淋巴细胞白血病.在CAR-T细胞中.CP: 癌症 癌症 癌症CP: 细胞生物学 细胞生物学收养免疫疗法采用免疫疗法.细胞进化的细胞进化.动态特征 动态特征 动态特征纵向研究是一种纵向研究.一个单细胞RNA测序.

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