青光眼的药物数量,眼睛表面障碍和治疗坚持之间的关系
Gustavo A Samico1, Ricardo Y Abe2, Tiago S Prata1
1Department of Ophthalmology and Visual Science, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
Arquivos brasileiros de oftalmologia
|October 18, 2023
概括
使用更多眼滴的青光眼患者经历了更严重的眼表面疾病和较差的治疗坚持. 增加的药物负担影响了催膜和遵守,尽管报告的副作用没有增加.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼研究研究 玻璃眼研究
- 眼睛表面疾病 眼睛表面疾病
背景情况:
- 青光眼的管理往往需要多次局部低血压眼滴.
- 多药对眼睛表面健康和对格洛科马治疗的坚持的影响尚未完全理解.
研究的目的:
- 为了调查所处方的青光眼药物数量与眼睛表面疾病之间的关系.
- 评估药物负担对青光眼治疗坚持性的影响.
主要方法:
- 一项涉及青光眼患者的横截面研究.
- 使用Keratograph 5M. 评估眼睛表面参数.
- 通过问卷评估眼睛表面疾病和治疗合规性.
主要成果:
- 使用三或四种类型的低血压眼药的患者显示,眼的高度显著降低.
- 在使用更多药物类别的患者中观察到较高的眼睛表面疾病指数得分.
- 在接受多疗法的患者中,由于缺乏滴滴而导致的忘记和障碍的得分更差.
结论:
- 增加局部玻璃眼瘤药物使用与较差的眼睛表面健康状况和减少治疗坚持有关.
- 较高的药物负担会对膜的稳定性和患者的服药性产生负面影响.
- 尽管眼睛表面发生了变化,但自我报告的副作用在各组之间没有显著差异.
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