胃神经内分泌瘤:什么时候需要手术治疗?
Ademar Caetano Assis Filho1, Valdir Tercioti Junior2, Nelson Adami Andreollo2
1Universidade Federal de Jataí - Jataí (GO), Brazil.
概括
经过手术治疗的胃神经内分泌瘤很少见,晚期病变往往需要干预. 本综述强调了关键的患者人口统计学,瘤特征和外科手术结果,强调了需要量身定制的管理来预防复发的必要性.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 内分泌学 在内分泌学.
背景情况:
- 胃神经内分泌瘤 (NETs) 是一组多样化的产生生物活性物质的瘤.
- 胃 NET 的治疗策略各不相同,取决于瘤的阶段和分类.
- 治疗方案包括内镜手术,手术,化疗,放射治疗和索马托斯塔丁类似物.
研究的目的:
- 识别和审查经过手术治疗的胃神经内分泌新生病例.
- 分析胃 NET 的临床表现,诊断结果和外科治疗.
主要方法:
- 对1983年至2018年间经过手术治疗的胃神经内分泌瘤患者的回顾性评估.
- 分析患者的人口统计学,症状,手术前内镜检查结果,手术程序和组织病理学结果.
主要成果:
- 分析了15名患者,主要是女性 (73.33%),平均年龄为55.93岁.
- 腹上疼痛是最常见的症状 (93.3%). 术前内镜显示,主要是单个病变 (60%),大小≥1.5厘米 (40%),胃 (53.33%),有 (60%) 和博尔曼III分类 (33.33%).
- 组织病理学证实了侵入性NETs (60%) 与血管淋巴细胞入侵 (80%). 免疫组织化学检测显示染色素A (60%) 和合成素 (66.7%) 呈阳性,基-67指数较低 (0-2%). 转移发生在20%的病例中,复发发生在20%的病例中.
结论:
- 胃神经内分泌瘤的发病率较低,在晚期的疾病中显示手术干预.
- 胃 NET 的有效管理需要个性化的方法来缓解复发和并发症.
- 这项研究强调了对胃神经内分泌瘤进行彻底评估和量身定制的手术策略的重要性.
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