视眼内压力24小时模式在眼中可疑存在于非洲人口中
Azeezat B Aderounmu1, Dupe S Ademola-Popoola2, Fatai O Olatunji2
1Department of Ophthalmology, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria.
Journal of glaucoma
|October 18, 2023
概括
在非洲,可疑患有青光眼的患者表现出更高的眼内压力 (IOP) 和更大的眼内压力波动,眼内压力高峰通常发生在诊所工作时间之外. 这凸显了对格洛科马诊断24小时监测的必要性.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼研究研究 玻璃眼研究
- 时间生物学 时间生物学
背景情况:
- 眼内压力 (IOP) 监测对于青光眼的诊断和管理至关重要.
- 了解24小时内血压的变化是必不可少的,特别是在不同的人群中.
- 之前的研究还没有完全描述非洲人群中白天IOP模式.
研究的目的:
- 在非洲人口中,在青光眼疑似患者和健康人群中,对眼内压力 (IOP) 的24小时变化进行表征.
- 为了比较初级开角玻璃眼 (POAG) 疑似患者和对照者之间的日间IOP模式.
主要方法:
- 一项涉及尼日利亚204名参与者 (102名POAG嫌疑人,102名对照) 的横截面分析研究.
- 在24小时内,每隔2小时进行一次全面的眼科检查和内膜压力测量,使用iCare调度仪.
- 组间平均峰值IOP,平均低谷IOP和IOP变化的比较.
主要成果:
- 与对照组 (17.17 mmHg) 相比,POAG疑似患者的平均峰值IOP (21.87 mmHg) 显著更高.
- 大多数POAG嫌疑人 (68.9%) 在午夜和上午8点之间,在典型的诊所时间之外,心脏压力达到峰值.
- 怀疑患有青光眼的患者24小时内血压变化 (83.3%> 6 mmHg) 比对照组 (73.6% ≤ 6 mmHg) 更大.
结论:
- 与健康对照人群相比,非洲血统的眼疑似患者的平均内血压显著更高,内血压波动更大.
- 在被怀疑患有青光眼的患者中,高峰IOP经常发生在标准诊所工作时间之外,这强调了延长监测的重要性.
- 这些发现强调了在非洲人群中诊断和管理眼时需要24小时的IOP评估.
更多相关视频
08:55Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments
Published on: April 24, 2020
3.1K
13:47Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis
Published on: June 3, 2018
9.4K
相关概念视频
Glaucoma: Overview
599
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
599
Open Angle Glaucoma: Treatment
459
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
459
Angle Closure Glaucoma: Treatment
536
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
536
